منابع مشابه
Antiangiogenic therapies in ovarian cancer
Angiogenesis plays a pivotal role in normal ovarian physiology as well as in the formation and progression of ovarian cancer. Several well-designed phase II and III trials studied the efficacy of antiangiogenic agents in advanced ovarian cancer. The results of these trials demonstrated significantly prolonged progression-free survival when antiangiogenic agents were used as a maintenance therap...
متن کاملAntiangiogenic therapies in ovarian cancer
Ovarian cancer is the fifth leading cause of cancer deaths among women and the leading cause of death from cancer of the gynecologic organs [1]. Often termed ‘the silent killer’, it usually produces no symptoms until it is in an advanced stage [2]. Few women have ovarian can‐ cer detected early and almost 75% of women diagnosed with ovarian cancer present at an advanced stage. Although the 5‐ye...
متن کاملTwo cases of clear cell ovarian cancer in young patients
Background: Ovarian cancer is the most common cause of cancer death worldwide. Incidence of ovarian cancer is more common in postmenopausal women. Premenopausal onset is rare and the present study described two cases of ovarian clear cell tumors in young women. Case Presentation: The patients presented with pelvic mass which was confirmed by sonography and laparotomy and final diagnosis was ...
متن کاملAntiangiogenic therapies in epithelial ovarian cancer.
BACKGROUND Angiogenesis is a critical component of tumor development and proliferation, and increased angiogenesis has been associated with a worse clinical outcome in a number of solid tumors, including ovarian cancer. Therefore, agents that target the angiogenic process are of considerable interest in the treatment of ovarian cancer. METHODS Studies evaluating the efficacy of antiangiogenic...
متن کاملTargeted Therapies in Epithelial Ovarian Cancer
Molecularly targeted therapy is relatively new to ovarian cancer despite the unquestionable success with these agents in other solid tumours such as breast and colorectal cancer. Advanced ovarian cancer is chemosensitive and patients can survive several years on treatment. However chemotherapy diminishes in efficacy over time whilst toxicities persist. Newer biological agents that target explic...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Medical Oncology
سال: 2021
ISSN: 1758-8359,1758-8359
DOI: 10.1177/17588359211008399